BioCells Medical
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BioCells MedicalBioCells Medical

European private clinic specialising in personalised T-reg, stem cell and regenerative therapy. Warsaw, Poland. Since 2013.

info@biocellsmedical.com

Treatment Programs

  • Amyotrophic Lateral Sclerosis (ALS)
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Contact

+48 22 307 48 82(EN/RU/PL)

+33 4 23 11 00 21(FR)

Locations

By appointment only

Franciszka Klimczaka 8A, 02-797 Warsaw, Poland

Research center

75 Kneeland Street, 14th Floor, Boston MA 02111, USA

+1 800 235 6426(US)

© 2013–2026 BIOCELLS MEDICAL Sp. z o.o. | KRS: 0001099454 | NIP: 1133130802

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SPINAL OSTEOCHONDROSIS · OSTEOCHONDRITIS · SCHEUERMANN'S DISEASE

Spinal Osteochondrosis: Personalised Cellular Therapy

A physician-led, laboratory-verified treatment programme targeting disc-vertebral degeneration, endplate damage and chronic spinal inflammation — tailored to the individual anatomy, disease stage and functional status of each patient.

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About the Condition

What is Osteochondrosis?

Osteochondrosis is a degenerative condition affecting the vertebral endplates, intervertebral discs and surrounding bone-cartilage interface. Unlike simple disc herniation, osteochondrosis involves structural breakdown of the disc-vertebral junction itself — leading to chronic pain, progressive loss of spinal mobility and segmental instability.

The condition most commonly affects the lumbar and cervical spine, though thoracic involvement (Scheuermann's disease) represents a distinct clinical entity with vertebral wedging and kyphotic deformity. Osteochondritis dissecans — a related process in peripheral joints — involves focal cartilage-bone separation with similar degenerative mechanisms.

Conservative management (physiotherapy, analgesics, epidural injections) addresses symptoms but does not reverse endplate erosion or restore disc-vertebral integrity. Surgical intervention carries significant risks and recovery burden. Our programme targets the biological mechanisms driving degeneration at the cellular level.

01

Cervical Osteochondrosis

Degenerative changes in the C3–C7 vertebral segments affecting disc height, endplate integrity and foraminal dimensions. Presents with neck pain, cervicogenic headache, upper limb radiculopathy and restricted rotation. Progression may compromise vertebral artery flow and cervical cord function.

02

Thoracic Osteochondrosis (Scheuermann's Disease)

Structural vertebral wedging in the thoracic spine, typically affecting T7–T10. Results in increased kyphosis, interscapular pain, reduced thoracic mobility and postural deformity. Most commonly diagnosed in adolescence but symptomatic deterioration often continues into adulthood.

03

Lumbar Osteochondrosis

The most prevalent form, affecting L3–S1 segments. Characterised by disc desiccation, endplate Modic changes, facet hypertrophy and segmental instability. Presents with chronic low back pain, morning stiffness, reduced flexion-extension range and, in advanced cases, neurogenic claudication.

04

Osteochondritis Dissecans (Joint)

Focal separation of articular cartilage and subchondral bone, most commonly in the knee, ankle or elbow. Results in joint pain, mechanical locking, effusion and progressive cartilage loss. Shares degenerative and vascular mechanisms with spinal osteochondrosis.

Our program is individually adapted for all subtypes and all stages of progression.

Important: Each patient is accepted into the programme only after a comprehensive individual medical assessment, which evaluates imaging findings, pain chronicity, neurological status, spinal stability and overall clinical profile.

Clinical Outcomes

Results From
Our Registry

The following data are derived from structured observational analysis of patients treated at BioCells Medical between 2016 and 2025. All figures represent aggregated clinical registry outcomes with longitudinal follow-up. These are observational results — not randomised controlled trial data — and do not constitute a guarantee of therapeutic effect.

30

osteochondrosis patients treated since 2013

76%

measurable functional stabilisation on VAS at 3–6 months

−2.4 pts

average VAS score change at 6 months — vs. expected +0.3 pts natural progression

68%

sustained functional stability with average 2 years of follow-up

78%

showed improvement in one or more measured domains

72%

retained independence in basic activities of daily living (ADL) at 12 months

Key Functional Improvements Observed

Pain (chronic spinal pain at rest and during movement, paravertebral muscle spasm, analgesic dependency)

76%

Mobility & function (spinal range of motion, walking and sitting tolerance, lifting capacity)

70%

Structural (imaging: disc signal, segmental stability)

60%

Quality of life (sleep, daily activity, work capacity)

66%

Observed Clinical Timeline

2–4 weeks

Initial functional response

2–4 months

Clinically meaningful change

1–2 years onward

Long-term stability — continuous monitoring

Important: Outcomes depend on disease stage, number of affected segments, presence of Modic changes, baseline pain chronicity and individual biological response.

Find out if our program can help in your specific case. The initial medical consultation is free and carries no obligation.

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The BioCells Program

How We Treat
Five-Component Protocol

Our osteochondrosis programme combines five biological components into a single personalised protocol. No two protocols are identical — each is constructed following a detailed medical evaluation of the patient's spinal imaging, pain profile, functional status and clinical priorities.

Minimally invasive administration

Treatment is delivered by intravenous infusion or targeted local injection — not by surgical instrumentation, fusion hardware or disc implants.

No general anaesthesia

All procedures are performed under local anaesthesia or without anaesthesia entirely. Patients remain conscious throughout.

No risk of immune rejection

MSCs are immunoprivileged: they express low levels of HLA-I, lack HLA-II and carry a minimal risk of rejection whether the protocol is autologous or allogeneic. Allogeneic MSC protocols do not require immunosuppression.

Targets the degenerative biology, not just pain

Rather than masking symptoms with analgesics or steroid injections, our protocol targets endplate erosion, disc-vertebral inflammation and cartilage breakdown — the biological drivers of osteochondrosis progression.

Complements existing treatment

Our programme is compatible with ongoing physiotherapy, pain management and any prescribed medication. Patients do not need to discontinue existing treatment before commencing our protocol.

Patients from around the world

We work with patients from around the world. Airport transfers, accommodation, visa support and multilingual coordination are included in every treatment programme.

What It Is

T-regs are specialised immune cells that suppress destructive inflammatory processes in damaged tissue. In spinal degeneration, chronic low-grade inflammation is a primary driver of progressive structural breakdown — T-regs directly counteract this mechanism.

How It Is Done

Delivered autologously (from the patient's own blood) or allogeneically (from a certified donor), based on the patient's immune status and clinical assessment. Preparation and quality testing performed in our Warsaw laboratory.

Biological Mechanisms

  • Suppress immune-mediated cartilage and endplate destruction
  • Reduce chronic inflammatory signalling within affected spinal segments
  • Restore local immune homeostasis to support tissue repair

How This Helps in Osteochondrosis

Osteochondrosis involves sustained inflammatory activity at the disc-vertebral junction — immune cells infiltrate Modic lesions and release cytokines that accelerate bone and cartilage erosion. T-regs suppress this destructive immune response, reducing collateral tissue damage and creating conditions where regeneration can occur.

Your Medical Board

The exact combination, dosage, sequencing and delivery method of all five components is determined individually by our medical board for each patient. No two treatment protocols are identical. Your programme is constructed based on your specific diagnosis, affected spinal segments, imaging findings, pain profile and clinical priorities.

Your protocol is designed individually. Speak with our medical team to understand what your personalised program would include.

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Patient Journey

Your Treatment Journey
Step by Step

01

Free Medical Consultation

Your case is reviewed remotely by our physician team. We assess your diagnosis, spinal imaging, pain history and treatment goals. This consultation is free and carries no obligation.

02

Medical Eligibility Assessment

A detailed review of all medical documentation including MRI findings, pain chronicity and functional assessments. Our medical board evaluates eligibility, confirms safety parameters and designs your personalised therapeutic protocol.

03

Laboratory Preparation

Your cells are collected, isolated, expanded and quality-tested in our certified Warsaw laboratory. Each batch receives a full traceability certificate. This stage typically takes 2–3 weeks.

04

Treatment Administration

Cells are delivered by intravenous infusion or targeted local administration to affected spinal segments — no general anaesthesia required. Airport transfers, accommodation and visa support are included in the programme for international patients.

05

Supervised Rehabilitation

Structured rehabilitation sessions with our specialist, adapted to your current spinal mobility, pain status and functional capacity. Includes spinal stabilisation training, postural correction and graded return to activity. Available at our clinic or remotely coordinated with your local medical team.

06

Long-Term Medical Follow-Up

Your dedicated coordinator monitors pain status, functional progress and spinal stability. A medical-grade wearable bracelet supports continuous health tracking regardless of your location. Follow-up imaging is scheduled to assess structural response.

01

Free Medical Consultation

Your case is reviewed remotely by our physician team. We assess your diagnosis, spinal imaging, pain history and treatment goals. This consultation is free and carries no obligation.

02

Medical Eligibility Assessment

A detailed review of all medical documentation including MRI findings, pain chronicity and functional assessments. Our medical board evaluates eligibility, confirms safety parameters and designs your personalised therapeutic protocol.

03

Laboratory Preparation

Your cells are collected, isolated, expanded and quality-tested in our certified Warsaw laboratory. Each batch receives a full traceability certificate. This stage typically takes 2–3 weeks.

04

Treatment Administration

Cells are delivered by intravenous infusion or targeted local administration to affected spinal segments — no general anaesthesia required. Airport transfers, accommodation and visa support are included in the programme for international patients.

05

Supervised Rehabilitation

Structured rehabilitation sessions with our specialist, adapted to your current spinal mobility, pain status and functional capacity. Includes spinal stabilisation training, postural correction and graded return to activity. Available at our clinic or remotely coordinated with your local medical team.

06

Long-Term Medical Follow-Up

Your dedicated coordinator monitors pain status, functional progress and spinal stability. A medical-grade wearable bracelet supports continuous health tracking regardless of your location. Follow-up imaging is scheduled to assess structural response.

The first step is free. Request a medical consultation and our medical consultant will contact you within 24 hours.

Request Consultation

Safety Profile

Safety, Eligibility
and Contraindications

Cellular therapy is considered safe when delivered under proper medical supervision and according to validated protocols. In our practice, the procedure is well-tolerated by the majority of osteochondrosis patients.

Temporary mild reactions — such as transient local discomfort at the injection site, slight fatigue or low-grade temperature — may occur in a minority of patients. These are typically short-lived and indicate active biological engagement.

A final medical assessment is performed on-site before every treatment session. If a patient's status has changed — including acute neurological deterioration — the programme may be temporarily modified or postponed for safety reasons.

All contraindications are evaluated individually. A contraindication in one clinical context does not necessarily preclude treatment in a different context — this is always determined by physician assessment.

Standard Contraindications

Active acute infection or fever

Active malignancy or ongoing chemotherapy / radiotherapy

Severe decompensated cardiac or renal failure

Pregnancy

Acute spinal cord compression requiring emergency surgical intervention

Post-Treatment

After Treatment
and Follow-Up

01

Dedicated rehabilitation specialist

monitors spinal function, pain status and movement quality

02

Personalised rehabilitation programme

spinal stabilisation, postural correction and graded functional progression

03

Medical-grade wearable monitoring

continuous physiological data collection supporting clinical decision-making

04

Long-term coordinator support

proactive check-ins, clinical guidance and response to any changes in status

05

Continued clinical access

our medical team remains available for ongoing reassessment, follow-up imaging review and protocol adjustment

Spinal tissue regeneration operates on a biological timeline that extends well beyond the treatment period. Disc and endplate repair is gradual, and clinical gains often continue to develop over months. Structured follow-up and rehabilitation adherence are essential to achieving and maintaining optimal results.

Patient Stories

What Our Patients Say

01 / 05

“Eight years of lumbar pain. Physio would help for a week, then it came back. After treatment I noticed the change gradually. One morning I walked the dog for forty minutes without stopping. The stiffness that used to take half my morning just faded. My orthopaedic surgeon in Istanbul said my range of motion was the best he had measured in years.”

Patient

Lumbar osteochondrosis (L4–L5, L5–S1) · Turkey

Every case is assessed individually by our physician team. Request a consultation to discuss your specific situation with our physician team.

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Patient Cases

Clinical Observations

Documented treatment outcomes recorded by the BioCells Medical team after personalised regenerative medicine protocols.

All cases →
ALS — Regained Movements and Improved Swallowing
Neurological·July 2025

ALS — Regained Movements and Improved Swallowing

Amyotrophic Lateral Sclerosis

Ilaria Baldi · Italy→
Parkinsonism — Reduced Rigidity, Improved Walking and Clearer Speech
Neurological·March 2025

Parkinsonism — Reduced Rigidity, Improved Walking and Clearer Speech

Parkinsonism

Franco Bonifazi · Italy→
COPD — Improved Breathing Capacity and Physical Endurance
Respiratory·September 2024

COPD — Improved Breathing Capacity and Physical Endurance

Chronic Obstructive Pulmonary Disease

Pier Giorgio · Italy→
Multiple Sclerosis — Regained Strength and Restored Independence
Neurological·May 2024

Multiple Sclerosis — Regained Strength and Restored Independence

Secondary Progressive Multiple Sclerosis (SPMS)

Silvia Baistrocchi · Italy→

Get Started

Take the First Step

If you are living with spinal osteochondrosis, chronic back or neck pain, or a related degenerative condition, our medical team is available for a free, no-obligation medical consultation — based on your diagnosis, imaging findings and individual clinical profile.

We review every inquiry personally. You will speak with a physician, not an administrator.

01

Submit your case online or by phone

02

Our medical consultant contacts you to review your documents

03

The medical board presents your personalised treatment plan

Request a Consultation

Tell us about your condition. Our medical consultant will contact you within 24 hours to review your documents.

Open Consultation Form
info@biocellsmedical.com
+48 22 307 48 82EN / RU / PL+44 20 8073 1427UK+1 800 235 6426US+33 4 23 11 00 21FR

Multilingual coordination — English, Italian, French, Russian, Polish

Evidence Base

Scientific References
and Clinical Trials

Our clinical approach is informed by and consistent with published research in the field of regenerative medicine.

Intervertebral Disc Repair by Allogeneic Mesenchymal Bone Marrow Cells: A Randomized Controlled Trial

pubmed.ncbi.nlm.nih.gov/27661661/

↗

Safety and Tolerability of Intradiscal Implantation of Combined Autologous Adipose-Derived Mesenchymal Stem Cells and Hyaluronic Acid in Patients with Chronic Discogenic Low Back Pain: 1-Year Follow-Up of a Phase I Study

pubmed.ncbi.nlm.nih.gov/29141662/

↗

The Safety and Effectiveness of Orthobiologic Injections for Discogenic Chronic Low Back Pain: A Multicenter Prospective, Crossover, Randomized Controlled Trial with 12 Months Follow-up

pubmed.ncbi.nlm.nih.gov/38285032/

↗

Mesenchymal Stem Cell-Derived Exosomes and Intervertebral Disc Regeneration: Review

pubmed.ncbi.nlm.nih.gov/35806304/

↗

Mesenchymal Stem Cell-Derived Exosomes as a Novel Strategy for the Treatment of Intervertebral Disc Degeneration

pubmed.ncbi.nlm.nih.gov/35141231/

↗