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BioCells MedicalBioCells Medical

European private clinic specialising in personalised regenerative and stem cell therapy. Warsaw, Poland. Since 2013.

info@biocellsmedical.com

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Franciszka Klimczaka 8A, 02-797 Warsaw, Poland

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SPASTIC · DYSKINETIC · ATAXIC · ALL GMFCS LEVELS · WARSAW, POLAND

Cerebral Palsy: Personalised Cellular Therapy

A physician-led programme targeting the neuroinflammatory, motor and developmental mechanisms of cerebral palsy — designed to improve motor function, reduce spasticity and support neurological development in children and adults.

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About the Condition

What is Cerebral Palsy?

Cerebral Palsy (CP) is a group of permanent movement disorders caused by non-progressive damage to the developing brain — most commonly occurring before, during or shortly after birth. It is the most common motor disability in childhood, affecting approximately 2–3 per 1,000 live births worldwide.

The brain injury itself does not worsen over time, but its consequences — spasticity, abnormal movement patterns, postural instability and secondary musculoskeletal problems — evolve as the child grows. Many children with CP also experience co-occurring conditions: epilepsy, speech and language difficulties, intellectual disability, visual impairment and chronic pain.

Conventional management focuses on physiotherapy, orthotics, botulinum toxin injections and orthopaedic surgery. These approaches manage symptoms but do not address the underlying neurological damage. Our programme targets the neuroinflammatory residue and impaired neural connectivity that persist after the original brain injury — the dimension that rehabilitation alone cannot reach.

01

Spastic Cerebral Palsy

The most common type, accounting for approximately 70–80% of cases. Characterised by increased muscle tone (hypertonia), stiff movements and exaggerated reflexes. Classified by distribution: hemiplegia (one side), diplegia (mainly legs) or quadriplegia (all four limbs). Spasticity results from damage to the motor cortex or corticospinal tracts.

02

Dyskinetic Cerebral Palsy

Characterised by involuntary, uncontrolled movements — dystonia (sustained twisting postures) or choreoathetosis (writhing, unpredictable movements). Results from damage to the basal ganglia. Muscle tone fluctuates between hypotonia and hypertonia. Accounts for approximately 10–15% of cases.

03

Ataxic Cerebral Palsy

The least common form, accounting for approximately 5% of cases. Characterised by poor balance, unsteady gait, difficulty with fine motor tasks and intention tremor. Results from damage to the cerebellum. Children often appear uncoordinated and have difficulty with precise voluntary movements.

Our program is individually adapted for all subtypes and all stages of progression.

Important: Each patient is accepted into the programme only after a comprehensive individual medical assessment evaluating CP subtype, GMFCS level, MRI findings, seizure history, current medication and rehabilitation status.

Our programme does not reverse established structural brain damage. It targets the chronic neuroinflammatory residue, impaired neural connectivity and metabolic dysfunction that limit functional recovery — with the objective of creating conditions for improved motor function, reduced spasticity and enhanced neurological development.

Clinical Outcomes

Results From
Our Registry

Based on 90 cerebral palsy patients (children and adults, all subtypes and GMFCS levels) treated at BioCells Medical, Warsaw, Poland, between 2014 and 2025. Internal clinical registry with longitudinal motor and developmental follow-up. These are observational results — not randomised controlled trial data — and do not constitute a guarantee of therapeutic effect.

70

Cerebral Palsy patients treated since 2013

73%

measurable functional improvement on GMFM at 3–6 months

+9.4 pts

average GMFM-66 score improvement at 6 months — vs. expected +1.5 pts annual natural gain

70%

sustained functional gains with average 3 years of follow-up

78%

showed improvement in one or more measured domains

72%

improved performance in basic activities of daily living (ADL) at 12 months

Key Functional Improvements Observed

Gross motor (gross motor function, mobility, postural control, trunk stability)

71%

Fine motor (fine motor coordination, hand function, object manipulation)

62%

Spasticity & muscle tone (reduction in spasticity, tone normalisation)

68%

Daily living & communication (speech clarity, oral motor control, daily functional independence)

67%

Observed Clinical Timeline

3–5 weeks

Initial functional response

3–6 months

Clinically meaningful change

2–3 years onward

Long-term stability — continuous monitoring

Important: Outcomes depend on CP subtype, GMFCS level, age at treatment, extent of brain injury and individual biological response. Children with higher baseline function (GMFCS I–III) generally show larger measurable improvements, though patients at all levels have demonstrated meaningful functional gains. Individual results may vary significantly.

Find out if our program can help in your specific case. The initial medical consultation is free and carries no obligation.

Request Consultation

Patient Stories

What Our Patients Say

01 / 05

“He took his first independent steps. Short, wobbly, but independent. Our son is five, spastic diplegia. He could stand holding furniture but walking on his own seemed unlikely. After the programme in Warsaw, something shifted. His physiotherapist in Amsterdam said it was the first meaningful jump since he started rehab at age two. He walks with orthoses now. Before, he was in a wheelchair full-time.”

Patient's mother

Spastic diplegia, GMFCS III · Netherlands

Every case is assessed individually by our physician team. Request a consultation to discuss your specific situation with our physician team.

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Patient Cases

Clinical Observations

Documented treatment outcomes recorded by the BioCells Medical team after personalised regenerative medicine protocols.

All cases →
ALS — Regained Movements and Improved Swallowing
Neurological·July 2025

ALS — Regained Movements and Improved Swallowing

Amyotrophic Lateral Sclerosis

Ilaria Baldi · Italy→
Parkinsonism — Reduced Rigidity, Improved Walking and Clearer Speech
Neurological·March 2025

Parkinsonism — Reduced Rigidity, Improved Walking and Clearer Speech

Parkinsonism

Franco Bonifazi · Italy→
COPD — Improved Breathing Capacity and Physical Endurance
Respiratory·September 2024

COPD — Improved Breathing Capacity and Physical Endurance

Chronic Obstructive Pulmonary Disease

Pier Giorgio · Italy→
Multiple Sclerosis — Regained Strength and Restored Independence
Neurological·May 2024

Multiple Sclerosis — Regained Strength and Restored Independence

Secondary Progressive Multiple Sclerosis (SPMS)

Silvia Baistrocchi · Italy→

The BioCells Program

How We Treat
Five-Component Protocol

Cerebral Palsy involves a fixed brain injury complicated by chronic neuroinflammation, impaired neural connectivity, ongoing oxidative stress and secondary musculoskeletal consequences. Our protocol addresses the neuroinflammatory and metabolic dimensions that limit recovery beyond what rehabilitation alone achieves. Each programme is constructed individually after a detailed evaluation of the patient's CP subtype, GMFCS level, age and functional priorities.

Targets what rehabilitation cannot reach

Physiotherapy trains muscles and movement patterns; our programme addresses the neuroinflammatory environment and impaired connectivity in the brain itself — the root limitation on motor recovery.

Maximises the neuroplasticity window

By reducing neuroinflammation and supporting neural connectivity, cellular therapy creates optimal conditions for the brain to respond to rehabilitation. Many families report that physiotherapy becomes more productive after treatment.

Minimally invasive administration

Treatment is delivered by intravenous infusion or targeted injection. Well-tolerated in paediatric patients, with protocols adapted for age and comfort.

Addresses spasticity at the neural level

Botulinum toxin and baclofen manage spasticity at the muscle level. Our programme addresses the dysfunctional motor circuits in the brain that generate excessive spastic signalling.

Compatible with existing therapy

Patients continue physiotherapy, occupational therapy, speech therapy, anticonvulsants and other current medications without interruption. Our programme integrates with the existing management plan.

No risk of immune rejection

MSCs are immunoprivileged: they express low levels of HLA-I, lack HLA-II and carry a minimal risk of rejection whether the protocol is autologous or allogeneic. Allogeneic MSC protocols do not require immunosuppression.

What It Is

MSCs are multipotent regenerative cells with well-documented immunomodulatory and neuroprotective properties. In cerebral palsy, they target the chronic neuroinflammation and microglial overactivation that persist long after the original brain injury — maintaining a hostile environment that prevents optimal neural recovery and plasticity.

How It Is Done

Cells are collected from the patient's own bone marrow (autologous, approximately 3-5 ml under local anaesthesia, adapted for paediatric patients) or sourced from a certified donor (allogeneic), depending on age and clinical indications. All cells are expanded, quality-controlled and tested in our certified Warsaw laboratory before administration.

Biological Mechanisms

  • Modulate chronic neuroinflammation persisting from the original perinatal brain injury
  • Reduce microglial overactivation in periventricular and cortical regions
  • Support the survival of existing neurons and promote neural plasticity
  • Create a neuroprotective environment conducive to motor learning and recovery

How This Helps in Cerebral Palsy

The original brain injury in CP happened months or years ago, but the neuroinflammatory response it triggered often persists indefinitely. This chronic inflammation suppresses neural plasticity — the brain's ability to form new connections and compensate for damaged areas. MSCs quiet this residual inflammation, which is why many families observe that rehabilitation becomes more effective after cellular therapy. The child's brain can finally respond to the motor learning that physiotherapy demands.

Your Medical Board

The exact combination, dosage, sequencing and delivery method of all five components is determined individually by our medical board for each patient. Paediatric protocols are adapted for age, weight and developmental stage. No two treatment protocols are identical. Your child's programme is constructed based on their specific CP subtype, GMFCS level, age and clinical priorities.

Your protocol is designed individually. Speak with our medical team to understand what your personalised program would include.

Request Consultation

Patient Journey

Your Treatment Journey
Step by Step

01

Free Medical Consultation

Your case is reviewed remotely by our physician team. We assess CP subtype, GMFCS level, MRI findings, seizure history and current rehabilitation programme. This consultation is free and carries no obligation.

02

Eligibility & Protocol Design

A detailed review of all medical documentation. Our medical board evaluates eligibility, confirms safety and designs a personalised protocol adapted to the patient's CP subtype, age, functional level and developmental priorities.

03

Laboratory Preparation

Cells are collected, isolated, expanded and quality-tested in our certified Warsaw laboratory. Each batch receives a full traceability certificate. This stage typically takes 2–3 weeks.

04

Treatment Administration

Cells are delivered by intravenous infusion or targeted local administration — no surgery, no general anaesthesia. Paediatric protocols are adapted for comfort and safety.

05

Motor & Developmental Rehabilitation

Structured rehabilitation sessions adapted to age and functional level — gross motor training, fine motor exercises, speech therapy support and postural management. Designed to maximise the neuroplasticity window following cellular therapy.

06

Long-Term Medical Follow-Up

Your dedicated coordinator monitors motor development, tracks GMFCS progression, provides clinical guidance and adjusts recommendations. A medical-grade wearable bracelet supports continuous tracking of movement patterns and functional milestones.

01

Free Medical Consultation

Your case is reviewed remotely by our physician team. We assess CP subtype, GMFCS level, MRI findings, seizure history and current rehabilitation programme. This consultation is free and carries no obligation.

02

Eligibility & Protocol Design

A detailed review of all medical documentation. Our medical board evaluates eligibility, confirms safety and designs a personalised protocol adapted to the patient's CP subtype, age, functional level and developmental priorities.

03

Laboratory Preparation

Cells are collected, isolated, expanded and quality-tested in our certified Warsaw laboratory. Each batch receives a full traceability certificate. This stage typically takes 2–3 weeks.

04

Treatment Administration

Cells are delivered by intravenous infusion or targeted local administration — no surgery, no general anaesthesia. Paediatric protocols are adapted for comfort and safety.

05

Motor & Developmental Rehabilitation

Structured rehabilitation sessions adapted to age and functional level — gross motor training, fine motor exercises, speech therapy support and postural management. Designed to maximise the neuroplasticity window following cellular therapy.

06

Long-Term Medical Follow-Up

Your dedicated coordinator monitors motor development, tracks GMFCS progression, provides clinical guidance and adjusts recommendations. A medical-grade wearable bracelet supports continuous tracking of movement patterns and functional milestones.

The first step is free. Request a medical consultation and our medical consultant will contact you within 24 hours.

Request Consultation

Safety Profile

Safety, Eligibility
and Contraindications

The programme is designed to be well-tolerated by paediatric and adult CP patients. Protocols are adapted for age, weight and any co-occurring conditions such as epilepsy. Mild transient reactions — brief fatigue or injection-site sensitivity — may occur and typically resolve within 24–48 hours.

Epilepsy co-occurs in approximately 25–35% of CP patients. Stable, medically managed epilepsy is not a contraindication to treatment. Patients with active, uncontrolled seizures require stabilisation before enrolment. Anticonvulsant medication is continued throughout the programme.

All contraindications are evaluated individually. A contraindication in one clinical context does not necessarily preclude treatment in a different context.

Standard Contraindications

Active acute infection or fever

Active malignancy or ongoing chemotherapy

Uncontrolled seizure activity (stable epilepsy is not a contraindication)

Pregnancy

Post-Treatment

After Treatment
and Follow-Up

01

Dedicated rehabilitation specialist

motor, developmental and speech rehabilitation adapted to age and GMFCS level

02

Medical-grade wearable monitoring

tracking movement patterns, functional milestones and activity levels

03

Long-term coordinator support

GMFCS retesting, developmental assessment and clinical guidance

04

Personalised home rehabilitation plan

exercises and activities designed to maintain and build on treatment gains

05

Continued clinical access

our medical team remains available for ongoing reassessment and protocol adjustment

Cerebral palsy involves a fixed brain injury, but its functional consequences evolve throughout life — particularly during childhood growth and development. Our follow-up programme tracks motor and developmental progress longitudinally, adapting recommendations to the patient's evolving clinical needs and rehabilitation goals.

Get Started

Cerebral Palsy Deserves More Than Symptom Management

Our medical team is available for a free consultation based on your child's CP subtype, GMFCS level and current rehabilitation programme. We work with patients at every functional level — from independently ambulatory to wheelchair-dependent.

We review every inquiry personally. You will speak with a physician, not an administrator.

01

Submit your case online or by phone

02

Our medical consultant contacts you to review your documents

03

The medical board presents your personalised treatment plan

Request a Consultation

Tell us about your condition. Our medical consultant will contact you within 24 hours to review your documents.

Open Consultation Form
info@biocellsmedical.com
+48 22 307 48 82EN / RU / PL+44 20 8073 1427UK+39 392 995 41 31IT+33 4 23 11 00 21FR

Multilingual coordination — English, Italian, French, Russian, Polish

Evidence Base

Scientific References
and Clinical Trials

Our clinical approach is informed by and consistent with published research in the field of regenerative medicine.

Cellular and Exosome-based Therapies in Neuroinflammatory Syndromes — ClinicalTrials.gov

clinicaltrials.gov/study/NCT07145502

↗

Evaluation of Stem/Stromal Cell Transplantation Safety and Efficacy in Children Diagnosed with Cerebral Palsy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials (2025)

pubmed.ncbi.nlm.nih.gov/40877893/

↗

Cord Blood Treatment for Children With Cerebral Palsy: Individual Participant Data Meta-Analysis (2025)

pubmed.ncbi.nlm.nih.gov/40210215/

↗

Motor Function and Safety After Allogeneic Cord Blood and Cord Tissue-Derived Mesenchymal Stromal Cells in Cerebral Palsy: An Open-Label, Randomized Trial (2022)

pubmed.ncbi.nlm.nih.gov/35811372/

↗