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BioCells MedicalBioCells Medical

European private clinic specialising in personalised regenerative and stem cell therapy. Warsaw, Poland. Since 2013.

info@biocellsmedical.com

Treatment Programs

  • Amyotrophic Lateral Sclerosis (ALS)
  • Multiple Sclerosis (MS)
  • Parkinson’s Disease
  • Multiple System Atrophy (MSA)
  • Peripheral Neuropathy
  • Muscular Dystrophy
  • Autism Spectrum Disorder (ASD)
  • Cerebral Palsy
  • All Diagnoses →

About

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Contact

+48 22 307 48 82(EN/RU/PL)

+39 392 995 41 31(IT)

+33 4 23 11 00 21(FR)

Locations

By appointment only

Franciszka Klimczaka 8A, 02-797 Warsaw, Poland

Research center

75 Kneeland Street, 14th Floor, Boston MA 02111, USA

© 2013–2026 BIOCELLS MEDICAL Sp. z o.o. | KRS: 0001099454 | NIP: 1133130802

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DIABETIC · AUTOIMMUNE · CIPN · CIDP · IDIOPATHIC · ALL TYPES EVALUATED

Peripheral Neuropathy: Personalised Cellular Therapy

A physician-led programme targeting the inflammatory and regenerative mechanisms of peripheral nerve damage — designed to reduce neuropathic pain, restore sensation and improve functional independence.

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About the Condition

What is Peripheral Neuropathy?

Peripheral neuropathy is damage to the peripheral nervous system — the network of nerves outside the brain and spinal cord that transmits signals between the CNS and the rest of the body. When these nerves are damaged, communication between the brain and muscles, skin and organs is disrupted.

Symptoms typically include burning, stabbing or shooting pain (often worse at night), numbness and tingling in the feet, legs and hands, loss of tactile and temperature sensation, muscle weakness and balance problems. In some forms, autonomic dysfunction affects digestion, blood pressure and bladder control.

Peripheral neuropathy has many causes and affects millions of people worldwide. Standard treatment focuses primarily on pain management — anticonvulsants, antidepressants and analgesics — which address symptoms but do not repair the underlying nerve damage. Our programme targets the biological mechanisms of nerve injury itself.

01

Diabetic Peripheral Neuropathy (DPN)

The most common cause of peripheral neuropathy worldwide, affecting approximately 50% of people with diabetes. Chronic hyperglycaemia damages peripheral nerves through a combination of direct metabolic toxicity, inflammation and vascular insufficiency. DPN is among the most responsive subtypes to MSC-based therapy in our clinical experience.

02

Chemotherapy-Induced Peripheral Neuropathy (CIPN)

A frequent and debilitating side effect of cancer treatment, caused by the neurotoxic effects of platinum-based agents, taxanes, vinca alkaloids and other chemotherapy drugs. CIPN can persist for months or years after completing cancer treatment and has very limited conventional treatment options.

03

Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

A progressive autoimmune demyelinating neuropathy in which the immune system attacks the myelin sheath of peripheral nerves. CIDP causes progressive weakness, numbness and impaired motor function. Standard treatment includes immunoglobulins and corticosteroids, but many patients experience incomplete response or significant side effects.

04

Idiopathic and Small Fiber Neuropathy

Nerve damage without an identified cause (idiopathic) or affecting unmyelinated pain and autonomic fibres (small fiber neuropathy). These forms are often underdiagnosed and undertreated. Patients frequently describe burning pain, temperature sensitivity and autonomic symptoms that standard nerve conduction studies may not detect.

05

Charcot–Marie–Tooth Disease (CMT)

Hereditary motor and sensory neuropathy causing progressive muscle weakness and atrophy, primarily in the feet, legs, hands and forearms. CMT is the most common inherited neurological disorder. While the genetic basis cannot be altered, our programme targets the inflammatory and metabolic mechanisms that influence the rate of functional decline.

Our program is individually adapted for all subtypes and all stages of progression.

Important: Each patient is accepted into the programme only after a comprehensive individual medical assessment evaluating neuropathy subtype, nerve conduction data, symptom pattern and medical history.

Our programme targets the biological mechanisms of nerve damage — inflammation, axonal degeneration and impaired nerve regeneration. It is designed to go beyond symptomatic pain management to support actual nerve fibre repair and functional recovery.

Clinical Outcomes

Results From
Our Registry

Based on 184 peripheral neuropathy patients (diabetic, autoimmune and idiopathic subtypes) treated at BioCells Medical, Warsaw, Poland, between 2013 and 2025. Internal clinical registry with longitudinal neurological follow-up. These are observational results — not randomised controlled trial data — and do not constitute a guarantee of therapeutic effect.

127

neuropathy patients treated since 2013

81%

measurable functional stabilisation on NRS at 3–6 months

−2.6 pts

average NRS score change at 6 months — vs. expected +0.4 pts natural progression

77%

sustained functional stability with average 3.5 years of follow-up

82%

showed improvement in one or more measured domains

78%

retained independence in basic activities of daily living (ADL) at 12 months

Key Functional Improvements Observed

Motor & strength (lower-limb strength, walking endurance, fine motor coordination)

73%

Sensory & pain (burning pain, dysesthesia, tactile and temperature sensation, nocturnal neuropathic discomfort)

80%

Autonomic (balance, fall risk, distal perception)

68%

Quality of life (sleep quality, daily independence, medication reduction)

72%

Observed Clinical Timeline

2–4 weeks

Initial symptomatic relief

2–4 months

Clinically meaningful change

2–3 years onward

Long-term stability — continuous monitoring

Important: Outcomes depend on neuropathy subtype, duration and severity of nerve damage, and individual biological response. Individual results may vary significantly.

Find out if our program can help in your specific case. The initial medical consultation is free and carries no obligation.

Request Consultation

Patient Stories

What Our Patients Say

01 / 05

“Three years of constant burning in my feet. I couldn’t sleep through a single night. After treatment, the pain went from an eight to maybe a three. I walk properly again. My endocrinologist in Milan said he honestly didn’t expect the improvement he measured.”

Patient

Diabetic Peripheral Neuropathy · Italy

Every case is assessed individually by our physician team. Request a consultation to discuss your specific situation with our physician team.

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Patient Cases

Clinical Observations

Documented treatment outcomes recorded by the BioCells Medical team after personalised regenerative medicine protocols.

All cases →
ALS — Regained Movements and Improved Swallowing
Neurological·July 2025

ALS — Regained Movements and Improved Swallowing

Amyotrophic Lateral Sclerosis

Ilaria Baldi · Italy→
Parkinsonism — Reduced Rigidity, Improved Walking and Clearer Speech
Neurological·March 2025

Parkinsonism — Reduced Rigidity, Improved Walking and Clearer Speech

Parkinsonism

Franco Bonifazi · Italy→
COPD — Improved Breathing Capacity and Physical Endurance
Respiratory·September 2024

COPD — Improved Breathing Capacity and Physical Endurance

Chronic Obstructive Pulmonary Disease

Pier Giorgio · Italy→
Multiple Sclerosis — Regained Strength and Restored Independence
Neurological·May 2024

Multiple Sclerosis — Regained Strength and Restored Independence

Secondary Progressive Multiple Sclerosis (SPMS)

Silvia Baistrocchi · Italy→

The BioCells Program

How We Treat
Five-Component Protocol

Peripheral neuropathy involves nerve damage, chronic inflammation and impaired regeneration. Our protocol addresses all three simultaneously. Each programme is constructed individually after a detailed evaluation of the patient’s neuropathy subtype, nerve damage profile and symptom pattern.

Goes beyond pain management

Standard neuropathy treatment masks pain without repairing nerves. Our protocol targets nerve regeneration, inflammation and vascular repair at the biological level.

Effective across multiple neuropathy subtypes

Diabetic, autoimmune, CIPN, CIDP, idiopathic and small fiber neuropathy all respond to targeted cellular and immunomodulatory intervention.

Minimally invasive administration

Treatment is delivered by intravenous infusion or targeted local injection. Well-tolerated across all age groups, including patients with diabetes and post-cancer status.

Compatible with existing pain medication

Patients do not need to discontinue gabapentin, pregabalin or other neuropathic pain medication. Our programme integrates with your existing pain management plan.

Particularly effective in diabetic neuropathy

DPN involves both inflammatory nerve damage and vascular insufficiency. MSC therapy addresses both mechanisms simultaneously — nerve regeneration and revascularisation.

Supports actual nerve fibre repair

Unlike symptomatic medication, our protocol supports Schwann cell function and axonal regeneration — the biological processes needed for real sensory and motor recovery.

What It Is

MSCs are multipotent regenerative cells with well-documented immunomodulatory and neuroprotective properties. In peripheral neuropathy, they serve a dual role: suppressing the chronic inflammation that damages nerve tissue and supporting the biological conditions necessary for axonal and myelin regeneration.

How It Is Done

Cells are collected from the patient’s own bone marrow (autologous) or sourced from a certified donor (allogeneic), depending on clinical indications. In diabetic neuropathy, targeted local delivery may be used alongside systemic infusion to maximise nerve regeneration in the most affected areas. All cells are processed in our certified Warsaw laboratory.

Biological Mechanisms

  • Modulate neuroinflammation within peripheral nerve tissue
  • Support axonal and myelin regeneration in damaged peripheral nerves
  • Promote revascularisation of ischaemic nerve tissue — particularly important in diabetic neuropathy
  • Protect existing nerve structures from further inflammatory damage

How This Helps in Peripheral Neuropathy

In diabetic neuropathy, chronic hyperglycaemia causes both direct nerve damage and vascular insufficiency that starves nerves of oxygen and nutrients. MSCs address both mechanisms — reducing inflammation, promoting new blood vessel formation around nerve tissue and supporting the conditions needed for actual nerve fibre regeneration rather than just pain suppression.

Your Medical Board

The exact combination, dosage, sequencing and delivery method of all five components is determined individually by our medical board for each patient. No two treatment protocols are identical. Your programme is constructed based on your specific neuropathy subtype, nerve damage profile and clinical priorities.

Your protocol is designed individually. Speak with our medical team to understand what your personalised program would include.

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Patient Journey

Your Treatment Journey
Step by Step

01

Free Medical Consultation

Your case is reviewed remotely by our physician team. We assess neuropathy type, nerve conduction studies, pain pattern and functional limitations. This consultation is free and carries no obligation.

02

Eligibility & Protocol Design

A detailed review of all medical documentation. Our medical board evaluates eligibility and designs a personalised protocol for your specific neuropathy subtype and nerve damage profile.

03

Laboratory Preparation

Cells are collected, isolated, expanded and quality-tested in our certified Warsaw laboratory. Each batch receives a full traceability certificate. This stage typically takes 2–3 weeks.

04

Treatment Administration

Cells are delivered by intravenous infusion and/or targeted local delivery — no surgery, no general anaesthesia.

05

Sensory & Motor Rehabilitation

Motor and sensory rehabilitation, balance training and fall prevention exercises. Adapted to your neuropathy subtype and current functional capacity.

06

Long-Term Medical Follow-Up

Your dedicated coordinator monitors nerve function, tracks pain levels, provides clinical guidance and adjusts recommendations. Repeat nerve conduction testing where appropriate to document functional change.

01

Free Medical Consultation

Your case is reviewed remotely by our physician team. We assess neuropathy type, nerve conduction studies, pain pattern and functional limitations. This consultation is free and carries no obligation.

02

Eligibility & Protocol Design

A detailed review of all medical documentation. Our medical board evaluates eligibility and designs a personalised protocol for your specific neuropathy subtype and nerve damage profile.

03

Laboratory Preparation

Cells are collected, isolated, expanded and quality-tested in our certified Warsaw laboratory. Each batch receives a full traceability certificate. This stage typically takes 2–3 weeks.

04

Treatment Administration

Cells are delivered by intravenous infusion and/or targeted local delivery — no surgery, no general anaesthesia.

05

Sensory & Motor Rehabilitation

Motor and sensory rehabilitation, balance training and fall prevention exercises. Adapted to your neuropathy subtype and current functional capacity.

06

Long-Term Medical Follow-Up

Your dedicated coordinator monitors nerve function, tracks pain levels, provides clinical guidance and adjusts recommendations. Repeat nerve conduction testing where appropriate to document functional change.

The first step is free. Request a medical consultation and our medical consultant will contact you within 24 hours.

Request Consultation

Safety Profile

Safety, Eligibility
and Contraindications

The programme is well-tolerated across neuropathy subtypes, including in patients with diabetes, post-cancer status, immune compromise or advanced age. Mild transient reactions — brief fatigue or injection-site sensitivity — may occur and typically resolve within 24–48 hours.

All eligibility is confirmed individually by our physician team before treatment. A final medical assessment is performed on-site before each session.

For patients with diabetic neuropathy, blood glucose management is reviewed as part of the treatment planning process. Glycaemic control influences treatment outcomes and is discussed with each patient.

Standard Contraindications

Active acute infection or fever

Active malignancy or ongoing chemotherapy

Severe decompensated cardiac or renal failure

Pregnancy

Post-Treatment

After Treatment
and Follow-Up

01

Dedicated rehabilitation specialist

sensory and motor recovery programme adapted to your neuropathy subtype

02

Balance and fall prevention training

particularly relevant in lower limb neuropathy

03

Medical-grade wearable monitoring

tracking activity, sleep and pain patterns

04

Long-term coordinator support

pain reassessment, nerve function tracking and clinical guidance

05

Continued clinical access

our medical team remains available for ongoing reassessment and protocol adjustment

Peripheral nerve regeneration is a gradual biological process. The period following treatment is when nerve repair consolidates into measurable functional improvement. Consistent monitoring allows us to track progress, adjust recommendations and respond to evolving clinical needs.

Get Started

Reduce Your Pain. Restore Your Function.

Our medical team is available for a free consultation based on your neuropathy type, current symptoms and nerve conduction data. We work with all peripheral neuropathy subtypes — diabetic, autoimmune, CIPN, CIDP and idiopathic.

We review every inquiry personally. You will speak with a physician, not an administrator.

01

Submit your case online or by phone

02

Our medical consultant contacts you to review your documents

03

The medical board presents your personalised treatment plan

Request a Consultation

Tell us about your condition. Our medical consultant will contact you within 24 hours to review your documents.

Open Consultation Form
info@biocellsmedical.com
+48 22 307 48 82EN / RU / PL+44 20 8073 1427UK+39 392 995 41 31IT+33 4 23 11 00 21FR

Multilingual coordination — English, Italian, French, Russian, Polish

Evidence Base

Scientific References
and Clinical Trials

Our clinical approach is informed by and consistent with published research in the field of regenerative medicine.

Efficacy and Safety of Stem Cells in Diabetic Peripheral Neuropathy: Systematic Review and Meta-Analysis

pubmed.ncbi.nlm.nih.gov/39563393/

↗

Stem Cell Therapy in Diabetic Polyneuropathy: Recent Advancements and Future Directions — Brain Sciences, 2023

pubmed.ncbi.nlm.nih.gov/36831798/

↗

Exploring the Role of Mesenchymal Stem Cell-Derived Exosomes in Diabetic and Chemotherapy-Induced Peripheral Neuropathy — Molecular Neurobiology, 2024

pubmed.ncbi.nlm.nih.gov/38252384/

↗

Mesenchymal Stem Cell Treatment for Peripheral Nerve Injury: A Narrative Review — Neural Regeneration Research, 2021

pubmed.ncbi.nlm.nih.gov/33818489/

↗

Schwann Cell-Derived Exosomes Enhance Axonal Regeneration in the Peripheral Nervous System — López-Verrilli et al., Glia, 2013

pubmed.ncbi.nlm.nih.gov/24038411/

↗

Cellular and Exosome-based Therapies in Neuroinflammatory Syndromes

clinicaltrials.gov/study/NCT07145502

↗